A 56-year-old female patient seeked medical advice because of mild fever and a face lesion of two-week duration. Her past medical history was significant for diabetes mellitus (managed with insulin), mild chronic renal insufficiency and breast cancer for which she underwent total right mastectomy 10 years ago. The patient also received radiation and chemotherapy at that time. She recently received again chemotherapy due to hepatic and bone metastases (the last chemotherapy regimen was one month ago). Physical examination showed a temperature of 37 degrees Celsius and a large, vegetating lesion on the nose with areas of honey-coloured and black areas (Figure 1). Routine laboratory testing showed: hematocrit 39.6%, hemoglobin 13 g/dL, white blood cell count 6.91 K per cubic mm, neutrophills 93.6%, glucose 622 mg/dL, creatinine 1.9 mg/dL, blood urea 96 mg/dL, and total bilirubin 1.36 mg/dL.